Unexplained Fatigue, Weight Gain, Dry Skin and More?

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Last Modified Date 2025-1-11T14:30:00+00:00

Understanding Hypothyroidism: Symptoms and Causes

If you're experiencing unexplained fatigue, weight gain, dry skin, or other persistent symptoms, consider the possibility of hypothyroidism. This condition occurs when the thyroid gland, a butterfly-shaped organ located in the neck, fails to produce sufficient thyroid hormones.

These hormones regulate various bodily functions, including metabolism, energy production, and hormonal balance. Let’s delve deeper into the symptoms, causes, and importance of identifying hypothyroidism early.

Weight Gain Thyroid
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How thyroid function can affect your weight

Hyperthyroidism occurs when the thyroid gland produces excessive amounts of hormones. Hyperthyroidism causes the thyroid gland to produce excessive amounts of thyroid hormone. 

When you have hyperthyroidism, you might experience symptoms like increased appetite, fatigue, nervousness, heart palpitations, muscle weakness, rapid heartbeat, and weight gain. If left untreated, hyperthyroidism could lead to serious health problems such as heart failure, kidney damage, and even death.

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Hypothyroidism is a disease characterized by low levels of thyroid hormone in the blood. Although it affects both men and women equally, it occurs most frequently in middle-aged adults. A person with hypothyroidism does not produce enough thyroid hormones to maintain average metabolic rates; therefore, the body needs to compensate for this deficiency by increasing its energy intake. 

This increased demand for energy causes individuals to eat more food than they usually would. In addition, metabolism slows down, causing the body to store more calories as fat.

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Topic Explanation / Details
Thyroid Hormones The thyroid gland produces three main hormones: thyroxine (T4), triiodothyronine (T3), and reverse T3 (rT3). T4 increases basal metabolic rate (BMR), rT3 promotes lipolysis (breakdown of fats), and T3 regulates protein synthesis and carbohydrate oxidation.
Hypothyroidism and Weight Gain

People with hypothyroidism burn fewer calories, retain fluid and sodium, and may gain weight. Symptoms include fatigue, dry skin, constipation, depression, hair loss, muscle cramps, menstrual irregularities, and weight gain. Hypothyroidism affects about 2% of the population.


Hyperthyroidism is caused by the overproduction of thyroid hormones. Symptoms include unintentional weight loss, anxiety, sweating, frequent bowel movements, difficulty sleeping, and muscle weakness.

Hypothyroidism vs Hyperthyroidism The key difference lies in hormone levels: hypothyroidism lowers hormone production, while hyperthyroidism increases it. Weight gain is typical in hypothyroidism, and weight loss is common in hyperthyroidism.
Neck Swelling (Goiter) Swelling in the neck may indicate an enlarged thyroid. An overactive thyroid (hyperthyroidism) or an underactive thyroid (hypothyroidism) can cause goiters. While often benign, goiters require medical monitoring to ensure proper thyroid function.
Feeling Too Cold or Hot Hypothyroidism often causes sensitivity to cold due to a low metabolism, while hyperthyroidism causes heat intolerance, excessive sweating, and an increased heart rate. Both conditions impact overall energy regulation.
Additional Hypothyroidism Symptoms Other symptoms include numbness or tingling in the hands, brittle nails, abnormal menstrual periods, depression, and cognitive difficulties. Hypothyroidism is sometimes called "the silent killer" because symptoms may be subtle initially.
Gender Differences in Thyroid Disorders Hyperthyroidism is more common in women than in men due to higher estrogen levels, which stimulate thyroid hormone production. Women are also diagnosed at an earlier age and may experience more pronounced symptoms.
Complications of Untreated Thyroid Disorders Untreated hypothyroidism can lead to severe fatigue, cognitive impairment, heart issues, and metabolic problems. Untreated hyperthyroidism may cause heart problems, bone loss, and, in extreme cases, death.
Importance of Diagnosis and Treatment Early diagnosis through blood tests (TSH, T3, T4) and imaging ensures proper management and treatment of thyroid disorders. Treatments include medications (such as thyroid hormone replacement or anti-thyroid drugs), surgery, or radioactive iodine therapy, depending on the specific condition.

Hypothyroidism and Weight Gain in Women

Hypothyroidism impacts weight gain in women due to several mechanisms. Low thyroid hormone levels slow metabolism, reduce calorie burn, and cause fluid retention, leading to bloating, especially in the face and legs.
 
Some women may experience altered appetite, increased hunger, or cravings. Muscle weakness caused by hypothyroidism can further reduce physical activity, making it harder to burn calories.
Topic Explanation / Details
Slowed Metabolism Thyroid hormones regulate metabolism, which controls the body's calorie burn. Low levels of thyroid hormones slow the metabolic rate, making weight loss more difficult even with a regular diet and exercise.
Fluid Retention Hypothyroidism can cause the body to retain water, leading to puffiness and weight gain. Common areas affected include the legs, hands, and face.
Altered Appetite Changes in thyroid function may increase hunger or cravings, leading women to consume more calories than necessary, which can contribute to weight gain.
Muscle Weakness Low thyroid hormone levels can lead to reduced muscle strength, making physical activity and calorie-burning exercises more challenging.
Long-Term Effects of Untreated Hypothyroidism Untreated hypothyroidism can have serious consequences. Long-term effects in women include increased risk of heart problems (high cholesterol, heart disease, heart failure), mental health issues (depression, anxiety, brain fog), infertility, miscarriage, weight gain, muscle weakness, joint pain, hair loss, dry skin, and increased sensitivity to cold.
Heart Problems Untreated hypothyroidism increases the risk of cardiovascular issues, including high cholesterol and heart disease, potentially leading to heart failure over time.
Mental Health Issues Hypothyroidism can contribute to depression, anxiety, and difficulty concentrating, impacting overall quality of life.
Reproductive Health Hypothyroidism can interfere with ovulation, causing infertility and increasing the risk of miscarriage if left untreated.
Other Long-Term Effects Women may also experience hair loss, dry and flaky skin, persistent weight gain, muscle weakness, joint pain, and increased sensitivity to cold temperatures.
Importance of Early Diagnosis Early detection and treatment of hypothyroidism with medication, lifestyle adjustments, and nutrition can prevent long-term complications and improve quality of life.

Sources & Credits: 

Foods to eat and avoid with hyperthyroidism
Hypothyroidism in Women: Understanding Common Symptoms
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